Selected studies
Interactive webtool for analyzing drug sensitivity and resistance associated with genetic signatures of cancer cell lines: Journal of Cancer Research and Clinical Oncology 2023
Database for queries of melanoma cohorts with molecular and clinical data: Pigment cell & melanoma research 2023
C-Reactive Protein and Lymphocyte-to-Monocyte Ratio Predict Recurrence in Stage III Melanoma Patients with Microscopic Sentinel Lymph Node Metastasis: Cancers 2023
TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entities: bioRxiv 2023
HLA Class II Loss and JAK1/2 Deficiency Coevolve in Melanoma Leading to CD4 T-cell and IFNγ Cross-Resistance: Clinical Cancer Research 2023
Identifying GPCRs involved in adipose tissue function using the innovative RNA-seq database FATTLAS: iScience 2023
Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity: Journal for Immunotherapy of Cancer 2022
Genetic and methylation profiles distinguish benign, malignant and spitzoid melanocytic tumors: International Journal of Cancer 2022
Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions: Cancers 2022
Genetic and methylation analysis of CTNNB1 mutations in benign and malignant melanocytic lesions: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT 2022
Cell-free mRNA circulating in the Plasma enables minimally invasive and Genotype-independent Therapy monitoring in Patients with Melanoma: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT 2022
Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype: Clinical and Translational Medicine 2022
Integrative genomic analyses of patient-matched intracranial and extracranial metastases reveal a novel brain-specific landscape of genetic variants in driver genes of malignant melanoma: Cancers 2021
The genetic landscape of intellectual disability and epilepsy in adults and the elderly: a systematic genetic work-up of 150 individuals: Genetics in Medicine 2021
Clinical characteristics and therapy response in unresectable melanoma patients stage IIIB-IIID with in-transit and satellite metastases: European Journal of Cancer 2021
Digital quantification of tumor PD-L1 predicts outcome of PD-1-based immune checkpoint therapy in metastatic melanoma: Frontiers in Oncology 2021
Tumor PD-L1-Positivity in medical and digital Quantification predicts a favorable Patient Outcome for a PD-1-based Immune Checkpoint-Blockade in metastatic Melanoma: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT 2021
Phenotype-tissue expression and exploration (PTEE) resource facilitates the choice of tissue for RNA-seq-based clinical genetics studies: BMC genomics 2021
GNAQ and GNA11 mutant nonuveal melanoma: a subtype distinct from both cutaneous and uveal melanoma: British Journal of Dermatology 2020
Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy: The Journal of clinical investigation 2020
Targeting the H3K4 demethylase KDM5B reprograms the metabolome and phenotype of melanoma cells: Journal of Investigative Dermatology 2019
Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma: European Journal of Cancer 2019
Application of circulating cell-free tumor DNA profiles for therapeutic monitoring and outcome prediction in genetically heterogeneous metastatic melanoma: JCO precision oncology 2019
Atypical fibroxanthoma and pleomorphic dermal sarcoma harbor frequent NOTCH1/2 and FAT1 mutations and similar DNA copy number alteration profiles: Modern Pathology 2018
Tumor CDKN2A-associated JAK2 loss and susceptibility to immunotherapy resistance: JNCI: Journal of the National Cancer Institute 2018
Targeted next generation sequencing of mucosal melanomas identifies frequent NF1 and RAS mutations: Oncotarget 2017
Chromosomal alterations predispose to immunotherapy resistance development in melanoma: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT 2017
Loss of heterozygosity in FANCG, FANCF and BRIP1 from head and neck squamous cell carcinoma of the oral cavity: International Journal of Oncology 2017
Single-strand DNA library preparation improves sequencing of formalin-fixed and paraffin-embedded (FFPE) cancer DNA: Oncotarget 2016
Targeted next generation sequencing reveals unique mutation profile of primary melanocytic tumors of the central nervous system: Journal of neuro-oncology 2016
Melanoma lesions independently acquire T-cell resistance during metastatic latency: Cancer research 2016
Diagnosing a primary leptomeningeal melanoma by gene mutation signature: The Journal of investigative dermatology 2016
Targeted Next Generation Sequencing Reveals Unique Mutation Profile of Primary Melanocytic Tumors of the Central Nervous System: LABORATORY INVESTIGATION 2016
Correction: High Inter-Individual Diversity of Point Mutations, Insertions, and Deletions in Human Influenza Virus Nucleoprotein-Specific Memory B Cells: Plos one 2015
Guanchochroma wildpretii gen. et spec. nov.(Ochrophyta) Provides New Insights into the Diversification and Evolution of the Algal Class Synchromophyceae: Plos one 2015
Routine amplicon sequencing for mutation screens in melanoma: JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT 2014
Genetic evolution of T-cell resistance in the course of melanoma progression: Clinical Cancer Research 2014
Synchroma pusillum sp. nov. and other new algal isolates with chloroplast complexes confirm the Synchromophyceae (Ochrophyta) as a widely distributed group of amoeboid algae: Protist 2012
Case study: enrichment of ancient mitochondrial DNA by hybridization capture: Ancient DNA: methods and protocols 2012
Genomic analysis of hepatitis B virus reveals antigen state and genotype as sources of evolutionary rate variation: Viruses 2011
Mitochondrial genomes reveal slow rates of molecular evolution and the timing of speciation in beavers (Castor), one of the largest rodent species: PloS one 2011
Genomic Analysis of Hepatitis B Virus Reveals Antigen State and Genotype as Sources of Evolutionary Rate Variation: 2011